ASME STP-PT-065 PDF
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Branch Leg Study for Bioprocessing Equipment
Description
Branch leg study for bpe focuses on the flow conditions required to ensure contact of the cleaning solution with the branched fittings.
Industry standards dead legs biopharmaceutical processing equipment place decade. leg defined area entrapment vessel piping run lead contamination product (asme bpe 2012 gr-8). l/d (ratio length diameter leg) six may historical maximum acceptable ratio, multiple studies promote designing less two. drivers reducing ratio cleanability fact today’s technology renders target two achievable. purpose document provide information flow conditions required displace air branches timely manner. displaced branched fitting, cleaning solution comes contact components cleaned-in-place (cip’ed) effective can occur. without cip solutions, no cleaning. focus ensure fittings – key requirement branch study focuses fittings.
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